Investigations of Some Biomarkers and Nutrients During Malaria Infection in Children in Sinar State-Sudan
Almojtaba Abd Alkhalig Ahmed Bakheet,
Asia Mohammed Elhassan
Issue:
Volume 3, Issue 3, June 2017
Pages:
24-30
Received:
25 October 2017
Accepted:
9 November 2017
Published:
13 December 2017
Abstract: Malaria is a distressing health problem that posses a socio-economic burden of considerable magnitude for communities in developing countries. It causes some immunological and hematological changes particularly inflammatory biomarkers and hemoglobin. Research is extensively required in this area to promote health services and to target radical solution to the problem. The study was done to investigate some biomarkers and nutrients during malaria infections in Sudanese children in Sinar State-Sudan and how these biomarkers may relate to factors such as age and hemoglobin which in children may be important in disease progression and control. Thirty-two samples of blood were collected from 16 malaria patient from Sinar hospital and 16 apparently healthy individuals from the same area as control group from which serum was separated. The investigations were carried out to estimate serum C-reactive protein (CRP), tumor necrosis factor alpha (TNF α) and serum magnesium as a nutrient in the two groups. High sensitive and highly specific techniques were used for biomarker determinations. Results showed that children of different age groups with Malaria have significantly high levels of C-reactive protein, mean ± SE 5.93 ±1.52).
Abstract: Malaria is a distressing health problem that posses a socio-economic burden of considerable magnitude for communities in developing countries. It causes some immunological and hematological changes particularly inflammatory biomarkers and hemoglobin. Research is extensively required in this area to promote health services and to target radical solu...
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